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A factor of safety of 1.5 is required to bring the confidence level to over 90 percent, for the reasons previously described. Therefore, in water usage terms, the design flow for each bedroom has been set at 150 gallons per day. This is based on

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OBJECTIVE To demonstrate the safety and effects of the gene therapy vector to be used in a proposed gene therapy clinical trial. DESIGN AND SETTING In a series of laboratory experiments, we modified the mitochondrial ND4 subunit of complex I in

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